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Marlayne Praska was the leader of the religious group "Children of the Ophan". She is credited with aiding in the creation of Sanctuarium with Mihai Lucescu, which would eventually become the birthplace of the Necrosi as a species.

Lucescu and Praska became leaders of a powerful legion of followers with a common hatred for their former oppressors as word of the safety offered by Lucescu's abode spread to hundreds of thousands of religious exiles who were persecuted for their beliefs. The refugees soon found a home at Sanctuarium, exchanging labour for safety and freedom.